MycroProcessor vs. GameBop is a YouTube Poop tennis match that took place between June 13, 2008 and January 4, 2009. The signature theme of this match was everything in each round being based almost entirely around a large multitude of puzzle/adventure games, with sources added including Riven, Myst, Alida, Mega Man ZX Advent, Myst V: End of Ages, Aura 2: The Sacred Rings, Myst III: Exile, Inkball, Pulseman, Myst IV: Revelation, Safecracker, Lighthouse, Jewels of the Oracle 2, Torin's Passage, 11th Hour, Island of Dr. Brain, RHEM 3, White Chamber, Submachine, MOTAS, Physiscus, Schizm, Crystal Key, Crystal Key 2: The Far Realm, D'ni Legacy, a trailer for Sentinel: Descendants in Time, Shivers, Shivers II, T'alvi, Terra Realms, Obsidan and Kings Quest VII.

This was the first complete match to be played by MycroProcessor and the 12th complete match to be played by GameBop. The match displays an incredible synergistic chemistry between the two players both in style and source usage, and as such was the beginning of a years-long close friendship between them. They would both go on to play each other several more times, both one-on-one and in a multitude of different multi-way combinations that had them volleying off of each other, as well as collaborating in Doubles matches, Triples matches, Team Tennis matches, and even a match against themselves where they made every round collaboratively while meeting up together in real life. Both players would reference and allude to this match several times in their subsequent work, notably a moment from the game Alida where the character Leval remarks "I hear somebody saying 21...or is it 22?" which was first played around with in the early rounds of this match. Often times this would manifest in both players joining a Chain or some other type of endless match or large multi-way specifically to claim Rounds 21 and Round 22 in advance.